2-methoxy-3-isopropyl Pyrazine
Synthétique
Green > Crisp Green > Burnt > Metallic
Crédits photo: ScenTree SAS
Other names :
Bean pyrazine ; 2-methoxy-3-(1-methylethyl)pyrazine
Volatility :
Head
Uses in perfumery :
2-methoxy-3-isopropyl Pyrazine is used in green tomato leaves notes, and can give a galbanum nuance to modern chypre perfumes. It can also be used as a replacer of Galbanum EO to bring a raw vegetables effect.
Natural availability :
2-methoxy-3-isopropyl Pyrazine can be found in common plants as aspargus, peas and cucumber, but is not extracted from these plants for its use in perfumes.
Year of discovery :
Data not available.
Other comments :
2-methoxy-3-isopropyl Pyrazine has a structure close to Galbazine, which has one more carbon atom. Their smell is quite equivalent, mixing a green galbanum note with a more pyrogenic and foody facet. Galbazine is anyway sweeter and fruitier.
Price Range :
€€€€
Stability :
Stable in perfumes and in various functional bases.
Crédits photo: ScenTree SAS
- Molecular formula :
- C8H12N2O
- Molecular Weight :
- 152,2 g/mol
- Density :
- 1
- Flash Point :
- 67°C
- Fusion Point :
- Donnée indisponible.
- Appearance :
- Pale yellow to yellow liquid
- Log P :
- 2,37
- Boiling Point :
- 123°C
- Detection Threshold :
- Donnée indisponible.
Synthesis route :
2-methoxy-3-isopropyl Pyrazine is part of a family of molecules which scent is close to peanuts as well as cooked and roasted fruits. Pyrazines are often obtained with a Gutknecht or Gastaldi condensation reaction, in both cases to condense two amines on two ketones, under the effect of an acid and oxidation. Here, one of the reagents contains both methoxy and isopropyl groups of the final molecule, while the other does not have any branches.
Another synthesis way, in two steps, consists in reacting Glycoxal with Norvaline amide hydrochloride, to form 2-hydroxy-3-propyl Pyrazine. The second step makes this intermediairy react with diazomethane, to provoke its ethylation.
Synthesis precursor :
2-methoxy-3-isopropyl Pyrazine is not a precursor for the synthesis of another olfactive compound.
Isomerism :
During the synthesis of 2-methoxy-3-isopropyl Pyrazine, two other compounds are formed : 2-methoxy-5-isopropyl Pyrazine and 2-methoxy-6-isopropyl Pyrazine. These two molecules have a similar smell as their isomer.
- EINECS number :
- 247-256-1
- FEMA number :
- 3358
- JECFA number :
- Donnée indisponible.
- FLAVIS number :
- 14.057
- Allergens :
- This ingredient does not contain any allergen.
- IFRA :
- This ingredient is not restricted
To learn more about IFRA's standards : https://ifrafragrance.org/safe-use/library
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