Cosmone®
Synthétique
Musky > Fresh Flowers > Green
Crédits photo: ScenTree SAS
Other names :
3-methyl-cyclotetradec-5-en-1-one ; 3-methyl-5-cyclotetradecen-1-one
Volatility :
Base
Uses in perfumery :
Cosmone® is generally used as a nitromusk replacer. It has a quite similar effect and makes it possible to nuance base notes, thanks to its fruity and green facets.
Natural availability :
Cosmone® does not exist on a natural state. Thus, it can't be used as extracted from a plant.
Year of discovery :
Discovered in 1998
Other comments :
Cosmone® can be used in very low quantity to bring an elegant effect.
Price Range :
€€€€
Stability :
Stable in perfumes and in diverse functional bases, except in liquid bleach and candle bases.
Crédits photo: ScenTree SAS
- Molecular formula :
- C15H26O
- Molecular Weight :
- 222,37 g/mol
- Density :
- 0,93
- Flash Point :
- >93°C
- Fusion Point :
- Donnée indisponible.
- Appearance :
- Colorless liquid
- Log P :
- 5,6
- Boiling Point :
- 258°C
- Detection Threshold :
- 0,1 ng/L air
Synthesis route :
Cosmone® is synthesized by a Wittig reaction in an alkaline medium, involving (4-carboxy-3-methylbutyl)triphenylphosphonium bromide and methyl 9-oxononanoate. This frist step leads to an ester, esterified using methanol (catalysor : paratoluensulfonic acid). Putting the ester in contact with pure sodium leads to a Bouveau-Blanc rearrangement, cycling the intermediary product into two acetates, linked by a positional isomery. To remove the ester groups from these two molecules, a reductive deacetoxylation is carried out with ammonia and calcium. This way, both Cosmone® isomers are obtained, to be separated by distillation.
Synthesis precursor :
Cosmone® is not used for the synthesis of another molecule of olfactive interest.
Isomerism :
Cosmone® has two diastereisomers, trans and cis. In perfumes, a blend of these two isomers is used, because they do not have a strong olfactive difference.
Cosmone® is initially a blend of two positional isomers, called Cosmone® I and II. Both are obtained during the synthesis, and can be separated by distillation.
Cosmone® is a constitutional isomer of some sandalwood alcohols as Javanol® or Polysantol®. Nevertheless, they do not have any olfactive similarities.
- EINECS number :
- 452-280-2
- FEMA number :
- Donnée indisponible.
- JECFA number :
- Donnée indisponible.
- FLAVIS number :
- Donnée indisponible.
- Allergens :
- This ingredient does not contain any allergen.
- IFRA :
- This ingredient is not restricted
To learn more about IFRA's standards : https://ifrafragrance.org/safe-use/library
ScenTree is solely responsible for the information provided here.
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