Skatole
Synthétique
Animalic > Feacal
Crédits photo: ScenTree SAS
Other names :
3-Methyl Indole ; 3-methyl-1H-indole ; 3-methyl-4,5-benzopyrrole ; 3-methylindole ; Scatol
Volatility :
Base
Uses in perfumery :
Skatole is used in small quantities in leather, woody notes, but less in floral notes than Indole. Brings an animalic facet to all types of accords.
Natural availability :
Skatole is found naturally in some cheeses, among others, but is very little extracted for its use in perfumery. Synthetic skatole is the most used.
Year of discovery :
1880
Other comments :
Skatole is more powerful and greedy than Indole but less floral.
Price Range :
€€€€
Stability :
This compound is well known for synthesizing Schiff bases by reacting espacially with aldehydes. These compounds can have an olfactive interest but are still a source of coloration in perfume concentrates and perfumes besides others. This is why this raw material is used is small quantities.
Crédits photo: ScenTree SAS
- Molecular formula :
- C9H9N
- Molecular Weight :
- 131,17 g/mol
- Density :
- Donnée indisponible.
- Flash Point :
- 132°C
- Fusion Point :
- 96°C
- Appearance :
- White solid
- Log P :
- 2,60
- Boiling Point :
- 266°C (à 255 mmHg)
- Detection Threshold :
- 0,2 ppb (0,00000002% !)
Synthesis route :
Skatole is part of the same family of molecules as Indole: the pyroles. These molecules can be synthesized in several ways. In the case of Skatole, a Fischer synthesis is adapted. This reaction consists in reacting phenylhydrazine with propanal, catalysed by a strong acid. Many other synthetic routes exist for this compound, such as the synthesis of Bischler-Möhlau, the Reissert or the Madelung synthesis among others.
Synthesis precursor :
Skatole is not a precursor to the synthesis of another compound of olfactory interest.
Isomerism :
Skatole does not have isomer used in perfumery.
- EINECS number :
- 201-471-7
- FEMA number :
- 3019
- JECFA number :
- 1304
- FLAVIS number :
- 14.004
- Allergens :
- This ingredient does not contain any allergen.
- IFRA :
- This ingredient is not restricted
To learn more about IFRA's standards : https://ifrafragrance.org/safe-use/library
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