Vertenex®

Synthesis route :

Vertenex® is synthesized by a first catalytic hydrogenation step of tertbutyl-phenol, at high temperature and pressure. Acetylation of the resulting compound is made by reaction with acetic anhydride and in the presence of an acid catalyst. For the hydrogenation phase, if nickel is used as a catalyst, the trans isomer is predominantly obtained. On the other hand, if the catalysis is made with rhodium, it is the cis isomer which is found in majority at the end of the reaction.

Synthesis precursor :

Vertenex® is not a precursor to the synthesis of another compound of olfactory interest.

Isomerism :

The trans isomer of Vertenex® has a very woody smell, while the cis isomer has a more fruity and floral smell. One of the positional isomers of Vertenex® is Verdox®, with a less woody smell. Citronellyl acetate and Menthanyl acetate are constitutional isomers of Verdox®. Their smell is distinctly different. Although also fruity, they do not have a woody note.