Geranyl acetate

Synthesis route :

Geranyl acetate can be synthesized from Geraniol by an esterification reaction using acetic acid or acetic anhydride, or from Myrcene, in two stages: an addition reaction with hydrochloric acid, catalysed by copper chloride II, then an acetolysis reaction using sodium ethanoate and a base such as triethylamine. This reaction allows to obtain both (E) Geranyl acetate and (Z) Neryl acetate, two diastereoisomers.

Synthesis precursor :

Geranyl acetate is not a precursor to the synthesis of another compound of olfactory interest.

Isomerism :

Neryl acetate, a (Z) diastereoisomer of Geranyl acetate, has a lighter, more terpenic smell than Geranyl acetate. Linalyl acetate, Terpenyl acetate and Isobornyl acetate are constitutional isomers of Geranyl acetate. However, Linalyl acetate and Terpenyl acetate are reminiscent of Bergamot EO, and Isobornyl acetate is reminiscent of pine.